S. Cameron is the elder daughter of Sir Reginald Adrian Berkeley Sheffield, 8th Baronet, a landowner descended from King Charles II of England and his first wife Annabel Lucy Veronica Jones. The Sheffield Baronetcy, of Normanby in the County of Lincoln, is a title in the Baronetage of Great Britain. It was created on 1 March 1755 for Charles Herbert Sheffield, the illegitimate son of John Sheffield, 1st Duke of Buckingham and Normanby. On the death of his half brother, the 2nd Duke, in 1735, he inherited the family estates including Buckingham House which was sold to George III in 1762 and Normanby Hall which latter remained the family residence until 1963.
Cameron is a distant cousin of Diana, Princess of Wales. Sir Reginald and Annabel married on November 1969; Samantha was born in 1971, Emily in 1973; the couple divorced in 1974. Her mother remarried William Waldorf Astor, 4th Viscount Astor.
Annabel Lucy Veronica Jones, Viscountess Astor is the daughter of Timothy Angus Jones and his wife Patricia David "Pandora" Clifford. Her mother was married secondly in 1961 to The Hon. Michael Astor, based in London. Her paternal grandparents were Sir Roderick Jones, the Chairman of Reuters, and the novelist Enid Bagnold, Lady Jones. Her mother Pandora Clifford was the daughter of The Hon. Sir Bede Edmund Hugh Clifford GCMG CB (son of William Hugh Clifford, 10th Baron Clifford of Chudleigh, a descendant of King Charles II of England) by his wife Alice Devin Gundry.
- Henry Astor (died 1833) was the brother of furrier and 18th century New York City real estate mogul John Jacob Astor.
Born in Walldorf, near Heidelberg to butcher Johann Jacob Astor and Maria Magdalena Vorfelder, Henry's primary venture was a butcher shop (in 1776) on the Bowery in Manhattan, from which, along with other investments he was able to establish sizeable wealth.
- John Jacob Astor (born Johann Jakob Astor; July 17, 1763 – March 29, 1848) was a German-American business magnate, merchant and investor who was the first prominent member of the Astor family and the first multi-millionaire in the United States. He was the creator of the first trust in America.
He went to the United States following the American Revolutionary War and built a fur-trading empire that extended to the Great Lakes region and Canada, and later expanded into the American West and Pacific coast. He also got involved in smuggling opium. In the early 19th century, he diversified into New York City real estate and later became a famed patron of the arts. At the time of his death in 1848, Astor was the wealthiest person in the United States.
- John Jacob Astor III (June 10, 1822 — February 22, 1890) was a financier and the eldest son of William Backhouse Astor, Sr. (son of John Jacob Astor and Sarah Todd) and Margaret Rebecca Armstrong (daughter of John Armstrong, Jr. and Alida Livingston). One of his uncles was John Jacob Astor, Jr.. John Jacob III became the wealthiest member of the Astor family in his generation and the founder of the English branch of the Astor family.
As a businessman, Astor dabbled in railroad investment, but was outsmarted by Cornelius "Commodore" Vanderbilt, Jr. and forced to yield control of the original New York Central Railroad line (from Albany to Buffalo) to him. His principal business interest was the vast Astor Estate real estate holdings in New York City, which he managed profitably and parsimoniously.
In 1846, Astor married Charlotte Augusta Gibbs (February 27, 1825 - December 12, 1887) of South Carolina. They had one son, William Waldorf Astor. In 1859 he built a home at 350 Fifth Avenue, today the street address of the Empire State Building. Later, he had an imposing vacation home, Beaulieu, built in Newport, Rhode Island. For twenty years, Charlotte supported a German industrial school.
- William Waldorf Astor, 1st Viscount Astor (March 31, 1848 — October 18, 1919) was a wealthy American attorney, and the only son of John Jacob Astor III. He moved with his family to the United Kingdom in 1891, became a citizen in 1899, and was made a peer in 1916. His childhood was spent in Germany and in Italy under the care of private tutors and a governess. He grew up in a cold and distant household. Upon the death of his father in early 1890, Astor inherited a personal fortune that made him the richest man in America.
That year, he initiated construction of the luxurious Waldorf Hotel, being built on the site of his former residence. (His cousin, John Jacob Astor IV built the adjoining Astoria Hotel in 1897, and the complex became the Waldorf-Astoria Hotel.) Astor moved with his wife and children to Great Britain. Astor made several business acquisitions while living in London. In 1892, he purchased the Pall Mall Gazette, and in 1893 established the Pall Mall Magazine. In 1911, he acquired The Observer. In 1912 he sold the Magazine, and in 1914 made a present of the Gazette and The Observer, with the building in Newton Street and its contents, to his son Waldorf Astor.
Postmaster General James Farley occupied two adjoining suites in the Waldorf-Astoria Towers during his tenure as the Chairman of the Board of Coca-Cola's International division from 1940 until his death in 1976, arguably one of the landmark's longest housed tenants.
- Waldorf Astor, 2nd Viscount Astor (May 19, 1879 – September 30, 1952) was an English politician and newspaper proprietor. A member of the prominent Astor family, Waldorf was born in New York City. He was the eldest son of William Waldorf Astor and Mary Dahlgren Paul (1858–1894); his youngest brother was John Jacob Astor V, later the first Baron Astor of Hever. During the military buildup in Germany in the 1930s, the Astors promoted entente with Germany, seen by some as appeasement of Hitler. Many of their associates felt sympathy for the state of Germany after World War I.
The Camerons are key members of the Chipping Norton set
- Racehorse trainer Charlie Brooks, and Rebekah Brooks (née Wade), former CEO of News International, editor of the The Sun and News of the World. Charlie was introduced to Rebekah by Jeremy Clarkson. The Brookses have holidayed with Elisabeth Murdoch and Matthew Freud on their yacht, and the Oppenheimer-Turners at their house in St Tropez.
- Steve Hilton and Rachel Whetstone. Hilton was Cameron's director of strategy and his wife, Rachel is the global head of communications and public policy for Google.
- Howard Stringer, chairman of Sony Corporation, appointed by David Cameron to his Business Advisory group.
- Elisabeth Murdoch, CEO of media production company Shine Limited, daughter of News Corporation CEO Rupert Murdoch, and sister of News Corporation executive and former chairman of BSkyB James Murdoch. Elizabeth Murdoch is married to Matthew Freud, owner of Freud Communications.
- Emily Oppenheimer Turner, journalist and painter, and William Turner, businessman. Emily is the granddaughter of Philip Oppenheimer, who ran the De Beers diamond empire; she is married to William Turner, director of The Hospital Group, Ltd. and former head of Sky Pictures, a division of BSkyB. William Turner worked as the head of Carlton films at Carlton Communications during David Cameron's time as director of corporate affairs at Carlton.
(all from Wikipedia)